Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2

The role of desmosomal cadherin desmocollin-2 (Dsc2) in regulating barrier function in intestinal epithelial cells (IECs) is not well understood. Here, we report the consequences of silencing Dsc2 on IEC barrier function in vivo using mice with inducible intestinal–epithelial-specific Dsc2 knockdown...

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Publicado en:Mol Biol Cell
Autores principales: Raya-Sandino, Arturo, Luissint, Anny-Claude, Kusters, Dennis H. M., Narayanan, Vani, Flemming, Sven, Garcia-Hernandez, Vicky, Godsel, Lisa M., Green, Kathleen J., Hagen, Susan J., Conway, Daniel E., Parkos, Charles A., Nusrat, Asma
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2021
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108520/
https://ncbi.nlm.nih.gov/pubmed/33596089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-12-0775
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