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Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration

The intestinal mucosa is lined by a single layer of epithelial cells that forms a tight barrier, separating luminal antigens and microbes from underlying tissue compartments. Mucosal damage results in a compromised epithelial barrier that can lead to excessive immune responses as observed in inflamm...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Flemming, Sven, Luissint, Anny-Claude, Kusters, Dennis H. M., Raya-Sandino, Arturo, Fan, Shuling, Zhou, Dennis W., Hasegawa, Mizuho, Garcia-Hernandez, Vicky, García, Andrés J., Parkos, Charles A., Nusrat, Asma
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185897/
https://ncbi.nlm.nih.gov/pubmed/31967937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-12-0692
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