DHODH and cancer: promising prospects to be explored

Human dihydroorotate dehydrogenase (DHODH) is a flavin-dependent mitochondrial enzyme catalyzing the fourth step in the de novo pyrimidine synthesis pathway. It is originally a target for the treatment of the non-neoplastic diseases involving in rheumatoid arthritis and multiple sclerosis, and is re...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Metab
Auteurs principaux: Zhou, Yue, Tao, Lei, Zhou, Xia, Zuo, Zeping, Gong, Jin, Liu, Xiaocong, Zhou, Yang, Liu, Chunqi, Sang, Na, Liu, Huan, Zou, Jiao, Gou, Kun, Yang, Xiaowei, Zhao, Yinglan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107416/
https://ncbi.nlm.nih.gov/pubmed/33971967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00250-z
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