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DHODH and cancer: promising prospects to be explored
Human dihydroorotate dehydrogenase (DHODH) is a flavin-dependent mitochondrial enzyme catalyzing the fourth step in the de novo pyrimidine synthesis pathway. It is originally a target for the treatment of the non-neoplastic diseases involving in rheumatoid arthritis and multiple sclerosis, and is re...
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| Publicado no: | Cancer Metab |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8107416/ https://ncbi.nlm.nih.gov/pubmed/33971967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00250-z |
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