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Development and Application of Novel Immunoassays for Eosinophil Granule Major Basic Proteins to Evaluate Eosinophilia and Myeloproliferative Disorders

BACKGROUND: During eosinophil differentiation, the granule eosinophil major basic protein 1 (eMBP1) is synthesized as a 32-kDa precursor form, referred to as proMBP1, which is processed into the 14-kDa mature form of eMBP1. The prevalence of these two forms of MBP1 in most pathological conditions re...

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Bibliographic Details
Published in:J Immunol Methods
Main Authors: Squillace, Diane L., Checkel, James L., Tefferi, Ayalew, Kita, Hirohito, Gleich, Gerald J
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107142/
https://ncbi.nlm.nih.gov/pubmed/33689807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2021.113015
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