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CircPVT1 up‐regulation attenuates steroid‐induced osteonecrosis of the femoral head through regulating miR‐21‐5p‐mediated Smad7/TGFβ signalling pathway

Steroid‐induced osteonecrosis of the femoral head (SIONFH) has been a common disease following corticosteroid therapy. Presently, we aim to explore the functions of circular RNA (circ) PVT1 in SIONFH rats and the underlying mechanism. Glucocorticoid (GC) was used to treat SD rats and bone marrow‐der...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Hao, Yangquan, Lu, Chao, Zhang, Baogang, Xu, Zhaochen, Guo, Hao, Zhang, Gaokui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107079/
https://ncbi.nlm.nih.gov/pubmed/33733589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16294
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