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CircPVT1 up‐regulation attenuates steroid‐induced osteonecrosis of the femoral head through regulating miR‐21‐5p‐mediated Smad7/TGFβ signalling pathway

Steroid‐induced osteonecrosis of the femoral head (SIONFH) has been a common disease following corticosteroid therapy. Presently, we aim to explore the functions of circular RNA (circ) PVT1 in SIONFH rats and the underlying mechanism. Glucocorticoid (GC) was used to treat SD rats and bone marrow‐der...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Hao, Yangquan, Lu, Chao, Zhang, Baogang, Xu, Zhaochen, Guo, Hao, Zhang, Gaokui
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107079/
https://ncbi.nlm.nih.gov/pubmed/33733589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16294
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