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CircPVT1 up‐regulation attenuates steroid‐induced osteonecrosis of the femoral head through regulating miR‐21‐5p‐mediated Smad7/TGFβ signalling pathway

Steroid‐induced osteonecrosis of the femoral head (SIONFH) has been a common disease following corticosteroid therapy. Presently, we aim to explore the functions of circular RNA (circ) PVT1 in SIONFH rats and the underlying mechanism. Glucocorticoid (GC) was used to treat SD rats and bone marrow‐der...

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Hao, Yangquan, Lu, Chao, Zhang, Baogang, Xu, Zhaochen, Guo, Hao, Zhang, Gaokui
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107079/
https://ncbi.nlm.nih.gov/pubmed/33733589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16294
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