miR-9-5p promotes wear-particle-induced osteoclastogenesis through activation of the SIRT1/NF-κB pathway

To explore the potential function of miR-9-5p in wear-particle-induced osteoclastogenesis, we examined the expression of SIRT1 and miR-9-5p in particle-induced osteolysis (PIO) mice calvariae and polyethylene (PE)-induced RAW 264.7 cells and found that SIRT1 expression was downregulated while miR-9-...

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Dades bibliogràfiques
Publicat a:3 Biotech
Autors principals: Zhang, Liang, Zhao, Weidong, Bao, Dongmei, Sun, Kening, Li, Peng, Gao, Zhihui, Lu, Zhidong
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107064/
https://ncbi.nlm.nih.gov/pubmed/33987074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-021-02814-8
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