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UHMWPE wear particles and dendritic cells promote osteoclastogenesis of RAW264.7 cells through RANK-activated NF-κB/MAPK/AKT pathways

Dendritic cells (DCs) were shown to enhance UHMWPE particle promoted osteoclastogenesis in RAW264.7 macrophages. This study aimed to elucidate the signaling network mediating the osteoclastogenic effects of UHMWPE particles and DCs. RAW264.7 cells were induced with UHMWPE particles and /or DC2.4 cel...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Zhang, Jianzhi, Zheng, Xin, Zhao, Fengchao, Liu, Xiaoyun, Pang, Yong, Cheng, Qi, Wang, Yi, Zhu, Yi, Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965995/
https://ncbi.nlm.nih.gov/pubmed/31966812
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