UHMWPE wear particles and dendritic cells promote osteoclastogenesis of RAW264.7 cells through RANK-activated NF-κB/MAPK/AKT pathways

Dendritic cells (DCs) were shown to enhance UHMWPE particle promoted osteoclastogenesis in RAW264.7 macrophages. This study aimed to elucidate the signaling network mediating the osteoclastogenic effects of UHMWPE particles and DCs. RAW264.7 cells were induced with UHMWPE particles and /or DC2.4 cel...

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Vydáno v:Int J Clin Exp Pathol
Hlavní autoři: Zhang, Jianzhi, Zheng, Xin, Zhao, Fengchao, Liu, Xiaoyun, Pang, Yong, Cheng, Qi, Wang, Yi, Zhu, Yi, Zhang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965995/
https://ncbi.nlm.nih.gov/pubmed/31966812
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