Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma

OBJECTIVES: The increasing success of Chimeric Antigen Receptor (CAR) T cell therapy in haematological malignancies is reinvigorating its application in many other cancer types and with renewed focus on its application to solid tumors. We present a novel CAR against glioblastoma, an aggressive, mali...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Abbott, Rebecca C, Verdon, Daniel J, Gracey, Fiona M, Hughes‐Parry, Hannah E, Iliopoulos, Melinda, Watson, Katherine A, Mulazzani, Matthias, Luong, Kylie, D’Arcy, Colleen, Sullivan, Lucy C, Kiefel, Ben R, Cross, Ryan S, Jenkins, Misty R
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106904/
https://ncbi.nlm.nih.gov/pubmed/33976881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1283
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