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Impact of high-dose folic acid supplementation in pregnancy on biomarkers of folate status and 1-carbon metabolism: An ancillary study of the Folic Acid Clinical Trial (FACT)

BACKGROUND: Periconceptional folic acid (FA) supplementation is recommended to prevent the occurrence of neural tube defects. Currently, most over-the-counter FA supplements in Canada and the United States contain 1 mg FA and some women are prescribed 5 mg FA/d. High-dose FA is hypothesized to impai...

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Détails bibliographiques
Publié dans:Am J Clin Nutr
Auteurs principaux: Murphy, Malia S Q, Muldoon, Katherine A, Sheyholislami, Hauna, Behan, Nathalie, Lamers, Yvonne, Rybak, Natalie, White, Ruth Rennicks, Harvey, Alysha L J, Gaudet, Laura M, Smith, Graeme N, Walker, Mark C, Wen, Shi Wu, MacFarlane, Amanda J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106758/
https://ncbi.nlm.nih.gov/pubmed/33675351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajcn/nqaa407
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