Distribution and metabolism of [(14)C]-resveratrol in human prostate tissue after oral administration of a “dietary-achievable” or “pharmacological” dose: what are the implications for anticancer activity?

BACKGROUND: The dietary polyphenol resveratrol prevents various malignancies in preclinical models, including prostate cancer. Despite attempts to translate findings to humans, gaps remain in understanding pharmacokinetic-pharmacodynamic relations and how tissue concentrations affect efficacy. Such...

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Dettagli Bibliografici
Pubblicato in:Am J Clin Nutr
Autori principali: Cai, Hong, Scott, Edwina N, Britton, Robert G, Parrott, Emma, Ognibene, Ted J, Malfatti, Michael, Khan, Masood, Steward, William P, Brown, Karen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106746/
https://ncbi.nlm.nih.gov/pubmed/33675348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajcn/nqaa414
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