In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury

Adult neurogenesis plays critical roles in maintaining brain homeostasis and in responding to neurogenic insults. However, the adult mammalian spinal cord lacks intrinsic capacity for neurogenesis. Here we show that spinal cord injury (SCI) unveils latent neurogenic potential of NG2+ glial cells, wh...

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Bibliographic Details
Published in:Cell Stem Cell
Main Authors: Tai, Wenjiao, Wu, Wei, Wang, Lei-Lei, Ni, Haoqi, Chen, Chunhai, Yang, Jianjing, Zang, Tong, Zou, Yuhua, Xu, Xiao-Ming, Zhang, Chun-Li
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106641/
https://ncbi.nlm.nih.gov/pubmed/33675690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2021.02.009
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