The p53 pathway controls SOX2-mediated reprogramming in the mouse adult spinal cord

Although the adult mammalian spinal cord lacks intrinsic neurogenic capacity, glial cells can be reprogrammed in vivo to generate neurons after spinal cord injury (SCI). How this reprogramming process is molecularly regulated, however, is not clear. Through a series of in vivo screens, we show here...

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Udgivet i:Cell Rep
Main Authors: Wang, Lei-Lei, Su, Zhida, Tai, Wenjiao, Zou, Yuhua, Xu, Xiao-Ming, Zhang, Chun-Li
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094368/
https://ncbi.nlm.nih.gov/pubmed/27732862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.038
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