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Parkinson's disease and mitophagy: an emerging role for LRRK2

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects around 2% of individuals over 60 years old. It is characterised by the loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain, which is thought to account for the major clinical symptom...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Singh, Francois, Ganley, Ian G.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106497/
https://ncbi.nlm.nih.gov/pubmed/33769432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190236
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