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Study on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology

BACKGROUND: Rhubarb, as a traditional Chinese medicine, is the preferred drug for the treatment of stagnation and constipation in clinical practice. It has been reported that rhubarb possesses hepatotoxicity, but its mechanism in vivo is still unclear. METHODS: In this study, the chemical components...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Li, Shanze, Wang, Yuming, Li, Chunyan, Yang, Na, Yu, Hongxin, Zhou, Wenjie, Chen, Siyu, Yang, Shenshen, Li, Yubo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106470/
https://ncbi.nlm.nih.gov/pubmed/33976539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S301417
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