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Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide
Triptolide (TP) is one of the important active components in Tripterygium wilfordii Hook. F., which shows strong anti-inflammatory and immunomodulatory effects. However, a large number of literature studies have reported that TP is the main component causing nephrotoxicity, and the mechanism of neph...
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| Veröffentlicht in: | Toxicol Res (Camb) |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7017871/ https://ncbi.nlm.nih.gov/pubmed/32110379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9tx00067d |
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