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Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide

Triptolide (TP) is one of the important active components in Tripterygium wilfordii Hook. F., which shows strong anti-inflammatory and immunomodulatory effects. However, a large number of literature studies have reported that TP is the main component causing nephrotoxicity, and the mechanism of neph...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Huang, Wei, Liu, Chuanxin, Xie, Lijuan, Wang, Yuming, Xu, Yanyan, Li, Yubo
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017871/
https://ncbi.nlm.nih.gov/pubmed/32110379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9tx00067d
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