Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin

The role of integrins, in particular αv integrins, in regulating insulin resistance is incompletely understood. We have previously shown that the αvβ5 integrin ligand milk fat globule epidermal growth factor like 8 (MFGE8) regulates cellular uptake of fatty acids. In this work, we evaluated the impa...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Datta, Ritwik, Lizama, Carlos O., Soltani, Amin K., Mckleroy, William, Podolsky, Michael J., Yang, Christopher D., Huynh, Tony L., Cautivo, Kelly M., Wang, Biao, Koliwad, Suneil K., Abumrad, Nada A., Atabai, Kamran
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106306/
https://ncbi.nlm.nih.gov/pubmed/33903257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2102171118
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