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Checkpoint inhibition in combination with an immunoboost of external beam radiotherapy in solid tumors (CHEERS): study protocol for a phase 2, open-label, randomized controlled trial

BACKGROUND: While the introduction of checkpoint inhibitors (CPIs) as standard of care treatment for various tumor types has led to considerable improvements in clinical outcome, the majority of patients still fail to respond. Preclinical data suggest that stereotactic body radiotherapy (SBRT) could...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Spaas, Mathieu, Sundahl, Nora, Hulstaert, Eva, Kruse, Vibeke, Rottey, Sylvie, De Maeseneer, Daan, Surmont, Veerle, Meireson, Annabel, Brochez, Lieve, Reynders, Dries, Goetghebeur, Els, Van den Begin, Robbe, Van Gestel, Dirk, Renard, Vincent, Dirix, Piet, Mestdagh, Pieter, Ost, Piet
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106163/
https://ncbi.nlm.nih.gov/pubmed/33962592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08088-w
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