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Novel compound heterozygous mutations in the CHST6 gene cause macular corneal dystrophy in a Han Chinese family

BACKGROUND: Macular corneal dystrophy (MCD), a rare autosomal recessive disorder, is caused by pathogenic mutations in the carbohydrate sulfotransferase 6 gene (CHST6) and is characterized by bilateral progressive stromal clouding and vision loss. Corneal transplantation is often necessary. This stu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Transl Med
Prif Awduron: Huang, Yanxia, Yuan, Lamei, Cao, Yanna, Tang, Renhong, Xu, Hongbo, Tang, Ziqian, Deng, Hao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: AME Publishing Company 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106006/
https://ncbi.nlm.nih.gov/pubmed/33987320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-7178
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