Intraductal administration of N-methyl-N-nitrosourea as a novel rodent mammary tumor model

BACKGROUND: Chemically induced animal models of breast cancer (BC) using N-methyl-N-nitrosourea (MNU) have been widely used in preclinical research. The conventional approach entails intraperitoneal (i.p) or intravenous injection of a carcinogen, leading to tumor induction at unpredictable locations...

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Bibliographic Details
Published in:Ann Transl Med
Main Authors: Gao, Dongcheng, Liu, Jianhua, Yuan, Jingping, Wu, Juan, Kuang, Xinwen, Kong, Deguang, Zheng, Weijie, Wang, Guannan, Sukumar, Saraswati, Tu, Yi, Chen, Chuang, Sun, Shengrong
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2021
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105867/
https://ncbi.nlm.nih.gov/pubmed/33987274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-21-1540
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