Nogo-B promotes epithelial-mesenchymal transition in lung fibrosis via PERK branch of the endoplasmic reticulum stress pathway

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal chronic pulmonary fibrosis disease and pathological mechanisms of fibrogenesis in IPF are still to be elucidated. Here, we investigated the potential role of Nogo-B in pulmonary fibrogenesis. METHODS: A mouse model of pulmonary fibrosis was...

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Gepubliceerd in:Ann Transl Med
Hoofdauteurs: Zhu, Ying, Yang, Meng, Li, Xue-Hui, Xu, Wu-Jian, Gao, Wei, Chen, Yu-Han, Li, Jian-Dong, Li, Qiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AME Publishing Company 2021
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105797/
https://ncbi.nlm.nih.gov/pubmed/33987261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-6143
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