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Unconventional voltage sensing in an inwardly rectifying potassium channel

Inwardly rectifying potassium channels are generally thought to achieve their physiological voltage dependence via an “extrinsic” mechanism involving voltage-dependent block by polyamines. A surprising finding of polyamine-independent gating of Kir4.1/Kir5.1 heteromeric channels suggests a mechanism...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Autor principal: Kurata, Harley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105720/
https://ncbi.nlm.nih.gov/pubmed/33956072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202112929
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