Hypochlorous acid-modified human serum albumin suppresses MHC class II - dependent antigen presentation in pro-inflammatory macrophages

Macrophages are innate immune cells that internalize and present exogenous antigens to T cells via MHC class II proteins. They operate at sites of infection in a highly inflammatory environment, generated in part by reactive oxygen species, in particular the strong oxidant hypochlorous acid (HOCl) p...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Ulfig, Agnes, Bader, Verian, Varatnitskaya, Marharyta, Lupilov, Natalie, Winklhofer, Konstanze F., Leichert, Lars I.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105673/
https://ncbi.nlm.nih.gov/pubmed/33940547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101981
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