The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis

Systemic lupus erythematosus is a highly complex and heterogeneous autoimmune disease mostly mediated by B cells. It is characterized by circulating self-reactive antibodies that deposit and form immune complexes in kidney, leading to irreparable tissue damage and resulting in lupus nephritis. In a...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Guiteras, Jordi, Ripoll, Élia, Bolaños, Núria, De Ramon, Laura, Fontova, Pere, Lloberas, Núria, Cruzado, Josep Maria, Aràn, Josep Maria, Aviñó, Anna, Eritja, Ramon, Gomà, Montse, Taco, Rosario, Grinyó, Josep Maria, Torras, Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2021
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105598/
https://ncbi.nlm.nih.gov/pubmed/33996261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.03.019
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