JAK3-STAT pathway blocking benefits in experimental lupus nephritis

BACKGROUND: Lupus nephritis (LN) is a complex chronic autoimmune disease of unknown etiology characterized by loss of tolerance against several self-antigens. Cytokines are known to be central players in LN pathogenesis. The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pa...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Ripoll, Èlia, de Ramon, Laura, Draibe Bordignon, Juliana, Merino, Ana, Bolaños, Nuria, Goma, Montse, Cruzado, Josep M., Grinyó, Josep M., Torras, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898357/
https://ncbi.nlm.nih.gov/pubmed/27278657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1034-x
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