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JAK3-STAT pathway blocking benefits in experimental lupus nephritis
BACKGROUND: Lupus nephritis (LN) is a complex chronic autoimmune disease of unknown etiology characterized by loss of tolerance against several self-antigens. Cytokines are known to be central players in LN pathogenesis. The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pa...
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| Veröffentlicht in: | Arthritis Res Ther |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4898357/ https://ncbi.nlm.nih.gov/pubmed/27278657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1034-x |
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