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YAP inhibits autophagy and promotes progression of colorectal cancer via upregulating Bcl-2 expression
Colorectal cancer (CRC) is one of the most aggressive and lethal cancers. The role of autophagy in the pathobiology of CRC is intricate, with opposing functions manifested in different cellular contexts. The Yes-associated protein (YAP), a transcriptional coactivator inactivated by the Hippo tumor-s...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8105309/ https://ncbi.nlm.nih.gov/pubmed/33963173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03722-8 |
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