The relationship between aldose reductase gene C106T polymorphism and the severity of retinopathy in Type 2 diabetic patients: A case–control study

BACKGROUND: Hyperglycemia over-activates glucose reduction to sorbitol by aldose reductase (ALR) leading to osmoregulation disruption and cellular damage that cause diabetic complications. We investigated the association of C106T polymorphism of ALR2 gene with the severity of diabetic retinopathy (D...

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Vydáno v:J Res Med Sci
Hlavní autoři: Abu-Hassan, Diala Walid, Al-Bdour, Muawyah D., Saleh, Ibraheem, Freihat, Mona, El-Khateeb, Mohammed
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer - Medknow 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103958/
https://ncbi.nlm.nih.gov/pubmed/34084181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/jrms.JRMS_250_20
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