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The relationship between aldose reductase gene C106T polymorphism and the severity of retinopathy in Type 2 diabetic patients: A case–control study

BACKGROUND: Hyperglycemia over-activates glucose reduction to sorbitol by aldose reductase (ALR) leading to osmoregulation disruption and cellular damage that cause diabetic complications. We investigated the association of C106T polymorphism of ALR2 gene with the severity of diabetic retinopathy (D...

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Detalhes bibliográficos
Publicado no:J Res Med Sci
Main Authors: Abu-Hassan, Diala Walid, Al-Bdour, Muawyah D., Saleh, Ibraheem, Freihat, Mona, El-Khateeb, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103958/
https://ncbi.nlm.nih.gov/pubmed/34084181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/jrms.JRMS_250_20
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