Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative fatal disorder in which motor neurons within the brain and spinal cord degenerate. A single infusion of mesenchymal stem cells (MSCs) delays disease progression by protecting motor neurons and restoring the blood-spinal cord barrier in the S...

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Dettagli Bibliografici
Pubblicato in:Mol Brain
Autori principali: Magota, Hirotoshi, Sasaki, Masanori, Kataoka-Sasaki, Yuko, Oka, Shinichi, Ukai, Ryo, Kiyose, Ryo, Onodera, Rie, Kocsis, Jeffery D., Honmou, Osamu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Micro Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103621/
https://ncbi.nlm.nih.gov/pubmed/33962678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00787-6
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