Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative fatal disorder in which motor neurons within the brain and spinal cord degenerate. A single infusion of mesenchymal stem cells (MSCs) delays disease progression by protecting motor neurons and restoring the blood-spinal cord barrier in the S...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Magota, Hirotoshi, Sasaki, Masanori, Kataoka-Sasaki, Yuko, Oka, Shinichi, Ukai, Ryo, Kiyose, Ryo, Onodera, Rie, Kocsis, Jeffery D., Honmou, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Micro Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103621/
https://ncbi.nlm.nih.gov/pubmed/33962678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00787-6
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