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Toxicology and Pharmacokinetics Study of Intradiscal Injection of Simvastatin in Rabbits

To test the pharmacokinetics and toxicology of whole organs and tissues after intradiscal injection of simvastatin in rabbits. To provide the information needed to support human clinical trials. Twelve male and twelve female rabbits were randomly divided into four groups: control group (0 mg/ml), lo...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Huang, Xiaodong, He, Wei, Wang, Weiheng, Fan, Quanchun, Ye, Xiaojian, Wu, Zenghui, Lin, Chia-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103611/
https://ncbi.nlm.nih.gov/pubmed/33967746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.582309
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