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The ocular toxicity and pharmacokinetics of simvastatin following intravitreal injection in mice
AIM: To investigate the retinal toxicity and pharmacokinetics of simvastatin intravitreally injected into mice. METHODS: Forty-eight 6-8-week-old C57BL/6J mice were used in this study. Simvastatin was intravitreally injected into the right eye of each mouse; the left eye was injected with vehicle an...
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Publicado no: | Int J Ophthalmol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
International Journal of Ophthalmology Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5596219/ https://ncbi.nlm.nih.gov/pubmed/28944193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2017.09.05 |
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