The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

The tumor microenvironment in brain metastases is characterized by high myeloid cell content associated with immune suppressive and cancer‐permissive functions. Moreover, brain metastases induce the recruitment of lymphocytes. Despite their presence, T‐cell‐directed therapies fail to elicit effectiv...

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發表在:EMBO Mol Med
Main Authors: Niesel, Katja, Schulz, Michael, Anthes, Julian, Alekseeva, Tijna, Macas, Jadranka, Salamero‐Boix, Anna, Möckl, Aylin, Oberwahrenbrock, Timm, Lolies, Marco, Stein, Stefan, Plate, Karl H, Reiss, Yvonne, Rödel, Franz, Sevenich, Lisa
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103101/
https://ncbi.nlm.nih.gov/pubmed/33755340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013412
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