Genetic Defects in DNAH2 Underlie Male Infertility With Multiple Morphological Abnormalities of the Sperm Flagella in Humans and Mice

Asthenozoospermia accounts for over 80% of primary male infertility cases. Reduced sperm motility in asthenozoospermic patients are often accompanied by teratozoospermia, or defective sperm morphology, with varying severity. Multiple morphological abnormalities of the flagella (MMAF) is one of the m...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Hwang, Jae Yeon, Nawaz, Shoaib, Choi, Jungmin, Wang, Huafeng, Hussain, Shabir, Nawaz, Mehboob, Lopez-Giraldez, Francesc, Jeong, Kyungjo, Dong, Weilai, Oh, Jong-Nam, Bilguvar, Kaya, Mane, Shrikant, Lee, Chang-Kyu, Bystroff, Christopher, Lifton, Richard P., Ahmad, Wasim, Chung, Jean-Ju
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103034/
https://ncbi.nlm.nih.gov/pubmed/33968937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.662903
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