Genetic Defects in DNAH2 Underlie Male Infertility With Multiple Morphological Abnormalities of the Sperm Flagella in Humans and Mice

Asthenozoospermia accounts for over 80% of primary male infertility cases. Reduced sperm motility in asthenozoospermic patients are often accompanied by teratozoospermia, or defective sperm morphology, with varying severity. Multiple morphological abnormalities of the flagella (MMAF) is one of the m...

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Foilsithe in:Front Cell Dev Biol
Main Authors: Hwang, Jae Yeon, Nawaz, Shoaib, Choi, Jungmin, Wang, Huafeng, Hussain, Shabir, Nawaz, Mehboob, Lopez-Giraldez, Francesc, Jeong, Kyungjo, Dong, Weilai, Oh, Jong-Nam, Bilguvar, Kaya, Mane, Shrikant, Lee, Chang-Kyu, Bystroff, Christopher, Lifton, Richard P., Ahmad, Wasim, Chung, Jean-Ju
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Cell and Developmental Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103034/
https://ncbi.nlm.nih.gov/pubmed/33968937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.662903
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