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Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation–Mass Spectrometry Assays

TMPRSS2-ERG gene fusion, a molecular alteration found in nearly half of primary prostate cancer cases, has been intensively characterized at the transcript level. However limited studies have explored the molecular identity and function of the endogenous fusion at the protein level. Here, we develop...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Proteomics
Päätekijät: Fu, Zhiqiang, Rais, Yasmine, Bismar, Tarek A., Hyndman, M. Eric, Le, X. Chris, Drabovich, Andrei P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102805/
https://ncbi.nlm.nih.gov/pubmed/33771697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcpro.2021.100075
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