Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease

Plasma biomarkers that reflect specific amyloid beta (Abeta) proteoforms provide an insight in the treatment effects of Alzheimer’s disease (AD) therapies. Our aim was to develop and validate ready-to-use Simoa ‘Amyblood’ assays that measure full length Abeta(1-42) and Abeta(1-40) and compare their...

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Publicado en:Sci Rep
Main Authors: Thijssen, Elisabeth H., Verberk, Inge M. W., Vanbrabant, Jeroen, Koelewijn, Anne, Heijst, Hans, Scheltens, Philip, van der Flier, Wiesje, Vanderstichele, Hugo, Stoops, Erik, Teunissen, Charlotte E.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102604/
https://ncbi.nlm.nih.gov/pubmed/33958661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89004-x
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