Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease

Plasma biomarkers that reflect specific amyloid beta (Abeta) proteoforms provide an insight in the treatment effects of Alzheimer’s disease (AD) therapies. Our aim was to develop and validate ready-to-use Simoa ‘Amyblood’ assays that measure full length Abeta(1-42) and Abeta(1-40) and compare their...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Thijssen, Elisabeth H., Verberk, Inge M. W., Vanbrabant, Jeroen, Koelewijn, Anne, Heijst, Hans, Scheltens, Philip, van der Flier, Wiesje, Vanderstichele, Hugo, Stoops, Erik, Teunissen, Charlotte E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102604/
https://ncbi.nlm.nih.gov/pubmed/33958661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89004-x
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