Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease

Plasma biomarkers that reflect specific amyloid beta (Abeta) proteoforms provide an insight in the treatment effects of Alzheimer’s disease (AD) therapies. Our aim was to develop and validate ready-to-use Simoa ‘Amyblood’ assays that measure full length Abeta(1-42) and Abeta(1-40) and compare their...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Thijssen, Elisabeth H., Verberk, Inge M. W., Vanbrabant, Jeroen, Koelewijn, Anne, Heijst, Hans, Scheltens, Philip, van der Flier, Wiesje, Vanderstichele, Hugo, Stoops, Erik, Teunissen, Charlotte E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102604/
https://ncbi.nlm.nih.gov/pubmed/33958661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89004-x
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