Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies

The need for high-affinity, SARS-CoV-2-specific monoclonal antibodies (mAbs) is critical in the face of the global COVID-19 pandemic, as such reagents can have important diagnostic, research, and therapeutic applications. Of greatest interest is the ~ 300 amino acid receptor binding domain (RBD) wit...

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Udgivet i:Sci Rep
Main Authors: Chapman, Asheley P., Tang, Xiaoling, Lee, Joo R., Chida, Asiya, Mercer, Kristina, Wharton, Rebekah E., Kainulainen, Markus, Harcourt, Jennifer L., Martines, Roosecelis B., Schroeder, Michelle, Zhao, Liangjun, Bryksin, Anton, Zhou, Bin, Bergeron, Eric, Bollweg, Brigid C., Tamin, Azaibi, Thornburg, Natalie, Wentworth, David E., Petway, David, Bagarozzi, Dennis A., Finn, M. G., Goldstein, Jason M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102525/
https://ncbi.nlm.nih.gov/pubmed/33958613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88809-0
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