Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies

The need for high-affinity, SARS-CoV-2-specific monoclonal antibodies (mAbs) is critical in the face of the global COVID-19 pandemic, as such reagents can have important diagnostic, research, and therapeutic applications. Of greatest interest is the ~ 300 amino acid receptor binding domain (RBD) wit...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Chapman, Asheley P., Tang, Xiaoling, Lee, Joo R., Chida, Asiya, Mercer, Kristina, Wharton, Rebekah E., Kainulainen, Markus, Harcourt, Jennifer L., Martines, Roosecelis B., Schroeder, Michelle, Zhao, Liangjun, Bryksin, Anton, Zhou, Bin, Bergeron, Eric, Bollweg, Brigid C., Tamin, Azaibi, Thornburg, Natalie, Wentworth, David E., Petway, David, Bagarozzi, Dennis A., Finn, M. G., Goldstein, Jason M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102525/
https://ncbi.nlm.nih.gov/pubmed/33958613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88809-0
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