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Palladium-Mediated C(γ)—H Functionalization of Alicyclic Amines

This paper describes a new method for the transannular functionalization of the γ-C-H bonds in alicyclic amines to install C(sp(3))–halogen, oxygen, nitrogen, boron, and sulfur bonds. The key challenge for this transformation is controlling the relative rate of C(γ)–H versus C(α)–H functionalization...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Aguilera, Ellen Y., Sanford, Melanie S.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102420/
https://ncbi.nlm.nih.gov/pubmed/33720500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202101782
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