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IDO1 Expression in Melanoma Metastases is Low and Associated with Improved Overall Survival

Indoleamine 2–3 dioxygenase 1 (IDO1) expression may contribute to immunologic escape by melanoma metastases. However, a recent clinical trial failed to identify any clinical benefits of IDO1 inhibition in patients with unresectable metastatic melanoma, and prior characterizations of IDO1 expression...

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Détails bibliographiques
Publié dans:Am J Surg Pathol
Auteurs principaux: Lynch, Kevin T., Gradecki, Sarah E., Kwak, Minyoung, Meneveau, Max O., Wages, Nolan A., Gru, Alejandro A., Slingluff, Craig L.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102301/
https://ncbi.nlm.nih.gov/pubmed/33208630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000001622
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