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Positive and Negative Regulation of Ferroptosis and Its Role in Maintaining Metabolic and Redox Homeostasis

Ferroptosis is a recently recognized regulated form of cell death characterized by accumulation of lipid-based reactive oxygen species (ROS), particularly lipid hydroperoxides and loss of activity of the lipid repair enzyme glutathione peroxidase 4 (GPX4). This iron-dependent form of cell death is m...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Sharma, Ankita, Flora, Swaran Jeet Singh
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102094/
https://ncbi.nlm.nih.gov/pubmed/34007410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/9074206
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