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An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference
Several distinct activities and functions have been described for chromatin insulators, which separate genes along chromosomes into functional units. Here, we describe a novel mechanism of functional separation whereby an insulator prevents gene repression. When the homie insulator is deleted from t...
Shranjeno v:
| izdano v: | PLoS Genet |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8102011/ https://ncbi.nlm.nih.gov/pubmed/33901190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009536 |
| Oznake: |
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