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A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication

Insulator sequences help to organize the genome into discrete functional regions by preventing inappropriate cross-regulation. This is thought to be mediated in part through associations with other insulators located elsewhere in the genome. Enhancers that normally drive Drosophila even skipped (eve...

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Detalhes bibliográficos
Main Authors: Fujioka, Miki, Wu, Xian, Jaynes, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730365/
https://ncbi.nlm.nih.gov/pubmed/19675129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.036467
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