Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets

Dissecting the evolution of memory B cells (MBCs) against SARS-CoV-2 is critical for understanding antibody recall upon secondary exposure. Here, we used single-cell sequencing to profile SARS-CoV-2-reactive B cells in 38 COVID-19 patients. Using oligo-tagged antigen baits, we isolated B cells speci...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Immunity
Κύριοι συγγραφείς: Dugan, Haley L., Stamper, Christopher T., Li, Lei, Changrob, Siriruk, Asby, Nicholas W., Halfmann, Peter J., Zheng, Nai-Ying, Huang, Min, Shaw, Dustin G., Cobb, Mari S., Erickson, Steven A., Guthmiller, Jenna J., Stovicek, Olivia, Wang, Jiaolong, Winkler, Emma S., Madariaga, Maria Lucia, Shanmugarajah, Kumaran, Jansen, Maud O., Amanat, Fatima, Stewart, Isabelle, Utset, Henry A., Huang, Jun, Nelson, Christopher A., Dai, Ya-Nan, Hall, Paige D., Jedrzejczak, Robert P., Joachimiak, Andrzej, Krammer, Florian, Diamond, Michael S., Fremont, Daved H., Kawaoka, Yoshihiro, Wilson, Patrick C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Elsevier Inc. 2021
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101792/
https://ncbi.nlm.nih.gov/pubmed/34022127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.05.001
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια