Profiling non-small cell lung cancer reveals that PD-L1 is associated with wild type EGFR and vascular invasion, and immunohistochemistry quantification of PD-L1 correlates weakly with RT-qPCR

Most lung cancer patients are diagnosed at an advanced stage, limiting their treatment options with very low response rate. Lung cancer is the most common cause of cancer death worldwide. Therapies that target driver gene mutations (e.g. EGFR, ALK, ROS1) and checkpoint inhibitors such anti-PD-1 and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Alwithenani, Akram, Bethune, Drew, Castonguay, Mathieu, Drucker, Arik, Flowerdew, Gordon, Forsythe, Marika, French, Daniel, Fris, John, Greer, Wenda, Henteleff, Harry, MacNeil, Mary, Marignani, Paola, Morzycki, Wojciech, Plourde, Madelaine, Snow, Stephanie, Marcato, Paola, Xu, Zhaolin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101740/
https://ncbi.nlm.nih.gov/pubmed/33956842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251080
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